assay of amylase test – GlycoDigest – Exoglycosidase Brief Guide

Advancing HIV Broadly Neutralizing Antibodies: From Discovery to the Clinic

Posted on November 3, 2021November 3, 2021 by Kristina

Regardless of substantial progress in confronting the worldwide HIV-1 epidemic since its inception within the 1980s, higher approaches for each therapy and prevention will probably be essential to finish the epidemic and stay a high public well being precedence. Antiretroviral remedy (ART) has been efficient in extending lives, however at a value of lifelong adherence to therapy. Broadly neutralizing antibodies (bNAbs) are directed to conserved...

Lowering the viscosity of a high-concentration antibody solution by protein-polyelectrolyte complex

Posted on November 3, 2021November 3, 2021 by Kristina

Excessive-concentration and low-viscosity antibody formulations are vital when administering these options subcutaneously (SC) resulting from limitations on injection quantity. Right here we present a way to lower the viscosity of monoclonal antibody resolution by protein-polyelectrolyte advanced (PPC) with poly-l-glutamic acid (polyE). The viscosity of omalizumab options was 90 cP on the focus of 150 mg/mL. Within the presence of 20-50 mM...